Journal article icon

Journal article

DNA repair fidelity of base excision repair pathways in human cell extracts.

Abstract:

Base excision repair (BER), responsible for the removal of altered DNA bases, is accomplished via two pathways that involve different subsets of repair enzymes and result in removal and replacement of one (short-patch BER) or several (long-patch BER) nucleotides. In this study, we constructed single-lesion containing DNA substrates that are predominantly repaired via one of the two pathways and investigated the fidelity of pathway specific repair in human whole cell extracts. We find that a s...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
DNA repair
Volume:
4
Issue:
2
Pages:
263-270
Publication date:
2005-02-05
DOI:
EISSN:
1568-7856
ISSN:
1568-7864
URN:
uuid:091e7ed3-f72f-45ef-8612-940b55b1a92d
Source identifiers:
131071
Local pid:
pubs:131071

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP