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Deep brain stimulation can regulate arterial blood pressure in awake humans.

Abstract:

The periaqueductal grey matter is known to play a role in cardiovascular control in animals. Cardiovascular responses to electrical stimulation of the periventricular/periaqueductal grey matter were measured in 15 awake human study participants following implantation of deep brain stimulating electrodes for treatment of chronic pain. We found that stimulation of the ventral periventricular/periaqueductal grey matter caused a mean reduction in systolic blood pressure of 14.2+/-3.6 mmHg in seve...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Neuroreport
Volume:
16
Issue:
16
Pages:
1741-1745
Publication date:
2005-11-05
DOI:
EISSN:
1473-558X
ISSN:
0959-4965
URN:
uuid:09189c02-a6ef-4c7a-b87b-ac3e30519bbb
Source identifiers:
106345
Local pid:
pubs:106345

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