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Combining sonodynamic therapy with chemoradiation for the treatment of pancreatic cancer

Abstract:

Treatment options for patients with pancreatic cancer are limited and survival prospects have barely changed over the past 4 decades. Chemoradiation treatment (CRT) has been used as neoadjuvant therapy in patients with borderline resectable disease to reduce tumour burden and increase the proportion of patients eligible for surgery. Antimetabolite drugs such as gemcitabine and 5-fluorouracil are known to sensitise pancreatic tumours to radiation treatment. Likewise, photodynamic therapy (PDT)...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jconrel.2021.07.020

Authors


Publisher:
Elsevier
Journal:
Journal of Controlled Release More from this journal
Volume:
337
Pages:
371-377
Publication date:
2021-07-16
Acceptance date:
2021-07-13
DOI:
EISSN:
1873-4995
ISSN:
0168-3659
Pmid:
34274382
Language:
English
Keywords:
Pubs id:
1187328
Local pid:
pubs:1187328
Deposit date:
2021-08-31

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