Journal article
Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever.
- Abstract:
-
The pharmacokinetics of oral and intravenous ofloxacin (7.5 mg.kg of body weight-1 given over 30 min) were studied in an open crossover study of 17 Vietnamese children, aged between 5 and 14 years, with acute uncomplicated typhoid fever. Following oral administration, the median (95% confidence interval [CI]) time to peak concentration of ofloxacin in serum (Cmax) was 1.7 h (1.4 to 1.9 h) and the mean (95% CI) Cmax was 5.5 mg.liter-1 (4.7 to 6.3 mg.liter-1) compared with a Cmax of 8.7 mg.lite...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Antimicrobial agents and chemotherapy
- Volume:
- 40
- Issue:
- 9
- Pages:
- 2167-2172
- Publication date:
- 1996-09-01
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
- Source identifiers:
-
45313
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:45313
- UUID:
-
uuid:09147cf4-20ad-4153-a6b9-57538d77f23c
- Local pid:
- pubs:45313
- Deposit date:
- 2012-12-19
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- Copyright date:
- 1996
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