Journal article
Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALS.
- Abstract:
-
BACKGROUND: The homogeneous genotype and stereotyped phenotype of a unique familial form of amyotrophic lateral sclerosis (ALS) (patients homozygous for aspartate-to-alanine mutations in codon 90 (homD90A) superoxide dismutase 1) provides an ideal model for studying genotype/phenotype interactions and pathological features compared with heterogeneous apparently sporadic ALS. The authors aimed to use diffusion tensor tractography to quantify and compare changes in the intracerebral corticospin...
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- Publication status:
- Published
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- Publisher copy:
- 10.1136/jnnp.2010.236018
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Authors
Bibliographic Details
- Journal:
- Journal of neurology, neurosurgery, and psychiatry
- Volume:
- 82
- Issue:
- 8
- Pages:
- 843-849
- Publication date:
- 2011-08-05
- DOI:
- EISSN:
-
1468-330X
- ISSN:
-
0022-3050
- URN:
-
uuid:0905a761-b61a-4d30-9ee2-1cd9fada86d6
- Source identifiers:
-
149729
- Local pid:
- pubs:149729
Item Description
Terms of use
- Copyright date:
- 2011
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