Journal article icon

Journal article

Templated scaffolds of cis- and trans-tetrahydrofuran gamma-amino acids: gamma-azido-beta-hydroxy-tetrahydrofuran-2-carboxylates from pentono-delta-lactones

Abstract:
Short syntheses of enantiomeric templated scaffolds of cis- and trans-tetrahydrofuran γ-amino acids from pentono-δ-lactones derived from arabinose and ribose are reported; an unexpectedly efficient synthesis of a templated tetrahydrofuran β-amino acid by azide displacement of a triflate β to an ester function proceeds with remarkably little elimination. These materials should allow evaluation of such peptidomimetics to induce predisposition towards secondary structures. © 2003 Elsevier Ltd. All rights reserved.
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
TETRAHEDRON LETTERS
Volume:
44
Issue:
31
Pages:
5847-5851
Publication date:
2003-07-28
DOI:
ISSN:
0040-4039
URN:
uuid:08f7ea8c-51f5-4c01-a6ee-1555974a94ba
Source identifiers:
38707
Local pid:
pubs:38707
Language:
English

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP