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Apparent Mendelian inheritance of breast and colorectal cancer: chance, genetic heterogeneity or a new gene?

Abstract:

It is not uncommon for cancer geneticists to be referred families with apparently Mendelian co-inheritance of breast and bowel cancer. Such families present a particular problem as regards the intensity of their screening for these diseases and the utility of genetic testing. Many 'breast-colon' cancer families probably result from chance clustering of two common cancers. Other 'breast-colon' cancer families may result from known cancer syndromes, such as hereditary breast-ovarian cancer or h...

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Publisher copy:
10.1023/a:1021101014264

Authors


Journal:
Familial cancer More from this journal
Volume:
1
Issue:
3-4
Pages:
189-195
Publication date:
2001-01-01
DOI:
EISSN:
1573-7292
ISSN:
1389-9600
Language:
English
Keywords:
Pubs id:
pubs:6224
UUID:
uuid:08f51d87-fc0a-456b-a6cb-6225218e5517
Local pid:
pubs:6224
Source identifiers:
6224
Deposit date:
2012-12-19

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