Journal article icon

Journal article

Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography

Abstract:

Background Optical coherence tomography (OCT) is a novel method of retinal in vivo imaging. In this study, we assessed the potential of OCT to yield histology-analogue sections in mouse models of retinal degeneration. Methodology/Principal Findings We achieved to adapt a commercial 3rd generation OCT system to obtain and quantify high-resolution morphological sections of the mouse retina which so far required in vitro histology. OCT and histology were compared in models with developmental def...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0007507

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
Public Library of Science
Journal:
PloS ONE More from this journal
Volume:
4
Issue:
10
Pages:
ARTN e7507
Publication date:
2009-10-19
Acceptance date:
2009-09-21
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:372118
UUID:
uuid:08e2fb4b-1427-49c9-93fb-530660f7952e
Local pid:
pubs:372118
Source identifiers:
372118
Deposit date:
2013-11-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP