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Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP.

Abstract:

Centrosomes have many important functions and comprise a 'mother' and 'daughter' centriole surrounded by pericentriolar material (PCM). The mother centriole recruits and organises the PCM and templates the formation of the daughter centriole. It has been reported that several important Drosophila PCM-organising proteins are recruited to centrioles from the cytosol as part of large cytoplasmic 'S-CAP' complexes that contain the centriole protein Sas-4. In a previous paper (Conduit et al., 2014...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.7554/elife.08483

Authors


Conduit, PT More by this author
Wainman, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
4
Issue:
November2015
Pages:
Article: e08483
Publication date:
2015
DOI:
EISSN:
2050-084X
ISSN:
2050-084X
URN:
uuid:08ca0ee3-6a15-474e-be98-8cdfac48bb82
Source identifiers:
579640
Local pid:
pubs:579640

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