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Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP.

Abstract:

Centrosomes have many important functions and comprise a 'mother' and 'daughter' centriole surrounded by pericentriolar material (PCM). The mother centriole recruits and organises the PCM and templates the formation of the daughter centriole. It has been reported that several important Drosophila PCM-organising proteins are recruited to centrioles from the cytosol as part of large cytoplasmic 'S-CAP' complexes that contain the centriole protein Sas-4. In a previous paper (Conduit et al., 2014...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/elife.08483

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
4
Issue:
November2015
Article number:
e08483
Publication date:
2015-01-01
Acceptance date:
2015-10-01
DOI:
EISSN:
2050-084X
ISSN:
2050-084X
Source identifiers:
579640
Language:
English
Keywords:
Pubs id:
pubs:579640
UUID:
uuid:08ca0ee3-6a15-474e-be98-8cdfac48bb82
Local pid:
pubs:579640
Deposit date:
2016-03-11

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