Journal article icon

Journal article

Spatial aspects of intracellular pH regulation in heart muscle.

Abstract:

Intracellular pH (pH(i)) is an important modulator of cardiac function. Because it is readily influenced by metabolic processes, pH(i) is controlled physiologically. Classical models of intracellular pH regulation comprise acid/base transport proteins expressed in the sarcolemma, acting in concert with intracellular buffers. These two processes are coupled via a diffusive movement of protons. Because intracellular H(+) buffering is high, H(i)(+)-diffusion occurs through a passive shuttling on...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Vaughan-Jones, RD More by this author
Spitzer, KW More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics, BHF Centre of Research Excellence
Journal:
Progress in biophysics and molecular biology
Volume:
90
Issue:
1-3
Pages:
207-224
Publication date:
2006
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
URN:
uuid:08c94050-9eff-4fb5-bc2b-042f7380ac21
Source identifiers:
106162
Local pid:
pubs:106162

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP