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Journal article

Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies.

Abstract:

The notch-signalling pathway regulates cell fate and differentiation through cell-cell communication. In recent years, several in vitro and in vivo studies have demonstrated that notch-signalling functions as a negative feedback mechanism downstream of the VEGF-signalling pathway that acts to finely shape the vascular network. Notch activation by the Jagged-1 and Delta-like 4 ligands regulates different steps of blood vessel development ranging from proliferation and survival of endothelial c...

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Publication status:
Published

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Publisher copy:
10.1007/s10456-008-9098-0

Authors


Journal:
Angiogenesis
Volume:
11
Issue:
1
Pages:
41-51
Publication date:
2008-01-01
DOI:
EISSN:
1573-7209
ISSN:
0969-6970
URN:
uuid:08c6f78e-2b17-45b9-8e1c-a938e3f47242
Source identifiers:
125234
Local pid:
pubs:125234

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