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Journal article

Rate of recombinational deletion among human endogenous retroviruses.

Abstract:

The fate of most human endogenous retroviruses (HERVs) has been to undergo recombinational deletion. This process involves homologous recombination between the flanking long terminal repeats (LTRs) of a full-length element, leaving a relic structure in the genome termed a solo LTR. We examined loci in one family, HERV-K(HML2), and found that the deletion rate decreased markedly with age: the rate among recently integrated loci was almost 200-fold higher than that among loci whose insertion pr...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.02216-06

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
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Journal:
Journal of virology
Volume:
81
Issue:
17
Pages:
9437-9442
Publication date:
2007-09-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:08c3c266-8131-4d8b-92ed-30dd341e3431
Source identifiers:
101068
Local pid:
pubs:101068

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