- Abstract:
-
The fate of most human endogenous retroviruses (HERVs) has been to undergo recombinational deletion. This process involves homologous recombination between the flanking long terminal repeats (LTRs) of a full-length element, leaving a relic structure in the genome termed a solo LTR. We examined loci in one family, HERV-K(HML2), and found that the deletion rate decreased markedly with age: the rate among recently integrated loci was almost 200-fold higher than that among loci whose insertion pr...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.02216-06
-
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- Journal:
- Journal of virology
- Volume:
- 81
- Issue:
- 17
- Pages:
- 9437-9442
- Publication date:
- 2007-09-05
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- URN:
-
uuid:08c3c266-8131-4d8b-92ed-30dd341e3431
- Source identifiers:
-
101068
- Local pid:
- pubs:101068
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Rate of recombinational deletion among human endogenous retroviruses.
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