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Clinical effectiveness and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: the CoBalT randomised controlled trial.

Abstract:

BACKGROUND: Only one-third of patients with depression respond fully to treatment with antidepressant medication. However, there is little robust evidence to guide the management of those whose symptoms are 'treatment resistant'. OBJECTIVE: The CoBalT trial examined the clinical effectiveness and cost-effectiveness of cognitive behavioural therapy (CBT) as an adjunct to usual care (including pharmacotherapy) for primary care patients with treatment-resistant depression (TRD) compared with usu...

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Publisher copy:
10.3310/hta18310

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Publisher:
National Co-ordinating Centre for HTA
Journal:
Health technology assessment (Winchester, England)
Volume:
18
Issue:
31
Pages:
1-viii
Publication date:
2014-05-05
DOI:
EISSN:
2046-4924
ISSN:
1366-5278
URN:
uuid:08c2dfa9-097a-49fd-a284-11dae00f63a8
Source identifiers:
491198
Local pid:
pubs:491198
Language:
English

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