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Corticotrophin releasing factor: effects on circulating gut and pancreatic peptides in man.

Abstract:

As a CRF-like peptide has been isolated from human gut, we investigated the effect of synthetic CRF-41 100 micrograms on gut and pancreatic peptides in six normal subjects. There was a significant rise in pancreatic polypeptide compared to a control infusion, but no change in plasma insulin, pancreatic glucagon, gastrin, somatostatin, motilin, neurotensin, gastric inhibitory peptide, or cholecystokinin was seen. In addition, there was no change in circulating met-enkephalin. We conclude that ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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Journal:
Clinical endocrinology
Volume:
20
Issue:
6
Pages:
725-729
Publication date:
1984-06-01
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
Source identifiers:
138661
Language:
English
Keywords:
Pubs id:
pubs:138661
UUID:
uuid:08bc2166-c11c-49e4-b506-86cb8a7ad505
Local pid:
pubs:138661
Deposit date:
2012-12-19

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