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Journal article

IGF-I levels rise and GH responses to GHRH decrease during long-term prednisone treatment in man.

Abstract:

Glucocorticoid excess is associated with a blunted GH response to GHRH. IGF-I levels in hypercortisolism are controversial and have been reported as low, normal or high. The aim of this study was to evaluate longitudinally time-dependent changes in the GH response to GHRH, IGF-I, IGFBP-3 and albumin values in patients during corticotherapy. Six patients received GHRH before and after one week and one month of prednisone administration (20-60 mg/d, orally). IGF-I, IGFBP-3 and albumin were dete...

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Publication status:
Published

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Publisher copy:
10.1007/bf03345472

Authors


Borges, MH More by this author
DiNinno, FB More by this author
Camacho-Hübner, C More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
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Journal:
Journal of endocrinological investigation
Volume:
22
Issue:
1
Pages:
12-17
Publication date:
1999-01-05
DOI:
EISSN:
1720-8386
ISSN:
0391-4097
URN:
uuid:08a96949-dbd9-4c6a-8ff5-617a0dcfe4eb
Source identifiers:
138487
Local pid:
pubs:138487

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