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Low level viral persistence after infection with LCMV: a quantitative insight through numerical bifurcation analysis.

Abstract:

Many important viruses persist at very low levels in the body in the face of host immunity, and may influence the maintenance of this state of 'infection immunity'. To analyse low level viral persistence in quantitative terms, we use a mathematical model of antiviral cytotoxic T lymphocyte (CTL) response to lymphocytic choriomeningitis virus (LCMV). This model, described by a non-linear system of delay differential equations (DDEs), is studied using numerical bifurcation analysis techniques f...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Mathematical biosciences More from this journal
Volume:
173
Issue:
1
Pages:
1-23
Publication date:
2001-09-01
DOI:
EISSN:
1879-3134
ISSN:
0025-5564
Language:
English
Keywords:
Pubs id:
pubs:17947
UUID:
uuid:08a94090-8391-4b2f-b8d8-552cea19bd22
Local pid:
pubs:17947
Source identifiers:
17947
Deposit date:
2012-12-19

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