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Journal article

Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival.

Abstract:

PURPOSE: To evaluate the occurrence and time course of hem- and lymphangiogenesis after normal-risk corneal transplantation in the mouse model and to test whether pharmacologic strategies inhibiting both processes improve long-term graft survival. METHODS: Normal-risk allogeneic (C57BL/6 to BALB/c) and syngeneic (BALB/c to BALB/c) corneal transplantations were performed and occurrence and time course of hem- and lymphangiogenesis after keratoplasty was observed, by using double immunofluores...

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Publication status:
Published

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Publisher copy:
10.1167/iovs.03-1380

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Journal:
Investigative ophthalmology and visual science
Volume:
45
Issue:
8
Pages:
2666-2673
Publication date:
2004-08-01
DOI:
EISSN:
1552-5783
ISSN:
0146-0404
Source identifiers:
102434

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