Journal article icon

Journal article

MHC class I chain-like gene A (MICA) and its associations with inflammatory bowel disease and peripheral arthropathy.

Abstract:

MHC class I chain gene A (MICA) is a non-classical Class I gene which is expressed on the surface of epithelia without beta 2-microglobulin. The gene is found in the major histocompatibility complex (MHC) in tight linkage disequilibrium with human leucocyte antigen-B (HLA-B). Its precise function is unknown, but it interacts with gamma delta T cells of the intestinal immune system. This region of the MHC has been implicated in inflammatory bowel disease (IBD) pathogenesis by recent associatio...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
Clinical and experimental immunology
Volume:
126
Issue:
3
Pages:
437-440
Publication date:
2001-12-05
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:087b85bd-cc13-4f57-9de5-51c5a51b0197
Source identifiers:
135413
Local pid:
pubs:135413

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP