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Journal article

Statistical analysis, trial design and duration in Alzheimer's disease clinical trials: a review.

Abstract:

BACKGROUND: The social and economic burden of Alzheimer's disease (AD) and its increasing prevalence has led to much work on new treatment strategies and clinical trials. The search for surrogate markers of disease progression continues but traditional parallel group trial designs that use well-established, but often insensitive, clinical outcome measures predominate. METHODS: We performed a systematic search across the Cochrane Library and PubMed abstracts published between January 2004 and...

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Publication status:
Published

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Publisher copy:
10.1017/s1041610211001116
Journal:
International psychogeriatrics / IPA More from this journal
Volume:
24
Issue:
5
Pages:
689-697
Publication date:
2012-05-01
DOI:
EISSN:
1741-203X
ISSN:
1041-6102
Language:
English
Keywords:
Pubs id:
pubs:457548
UUID:
uuid:08779120-b2aa-44af-8885-4eb9dc70b2e2
Local pid:
pubs:457548
Source identifiers:
457548
Deposit date:
2014-05-13

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