Journal article

Fluorine in medicinal chemistry.

Abstract:: It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.

Publication status:: Published

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APA Style

Purser, S., Moore, P., Swallow, S., & Gouverneur, V. (2008). Fluorine in medicinal chemistry. Chemical Society Reviews, 37(2), 320–330.

MLA Style

Purser, S, et al. “Fluorine in Medicinal Chemistry.” Chemical Society Reviews, vol. 37, no. 2, 2008, pp. 320–30.

Chicago Style

Purser, S, P Moore, S Swallow, and V Gouverneur. 2008. “Fluorine in Medicinal Chemistry.” Chemical Society Reviews 37 (2): 320–30.
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Publisher copy:: 10.1039/b610213c

Authors

+ Purser, S More by this author

Role:: Author

+ Moore, P More by this author

Role:: Author

+ Swallow, S More by this author

Role:: Author

+ Gouverneur, V More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: Chemical Society reviews More from this journal
Volume:: 37
Issue:: 2
Pages:: 320-330
Publication date:: 2008-02-01
DOI:: 10.1039/b610213c
EISSN:: 1460-4744
ISSN:: 0306-0012

Language:: English
Keywords:: Humans

Stereoisomerism

Chemistry, Pharmaceutical

Drug Design

Molecular Structure

Hydrocarbons, Fluorinated
Pubs id:: pubs:34101
UUID:: uuid:0869251e-0aeb-482f-8b46-1c3105ca2958
Local pid:: pubs:34101
Source identifiers:: 34101
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_0869251e0aeb482f8b461c3105ca2958

Terms of use

Copyright date:: 2008

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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