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Journal article

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals.

Abstract:

BACKGROUND: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain.OBJECTIVE: The aim was to assess the effects of treatment with B vitamins compared with placebo, when administered for several years, on composite domains of cognitive function, global cognitive function, and cognitive aging.DESIGN: A meta-analysis was conducted by using data combined from 11 large trials in 22,000 partici...

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Publication status:
Published

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Publisher copy:
10.3945/ajcn.113.076349

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
Publisher:
American Society for Nutrition
Journal:
American journal of clinical nutrition
Volume:
100
Issue:
2
Pages:
657-666
Publication date:
2014-06-01
DOI:
EISSN:
1938-3207
ISSN:
0002-9165
Language:
English
Keywords:
Pubs id:
pubs:471121
UUID:
uuid:084dcf3c-b257-4f80-b977-82dc18a59d89
Local pid:
pubs:471121
Source identifiers:
471121
Deposit date:
2014-07-02

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