Journal article
Using a Markov model and real-world evidence to identify the most cost-effective cholesterol treatment escalation threshold for the secondary prevention of cardiovascular disease
- Abstract:
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Background
Despite the decreased risk of cardiovascular disease (CVD) with statins, there remains an unfulfilled clinical need to prevent CVD events and premature mortality through further cholesterol-modifying interventions. In people with established CVD taking a statin, lipid therapy escalation to reduce low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (non-HDL-C) levels may lower the risk of CVD hospital admissions and improve su...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 952.5KB, Terms of use)
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- Publisher copy:
- 10.1007/s40258-025-00977-6
Authors
- Publisher:
- Springer Nature
- Journal:
- Applied Health Economics and Health Policy More from this journal
- Volume:
- 23
- Issue:
- 5
- Pages:
- 869–883
- Publication date:
- 2025-05-24
- Acceptance date:
- 2025-05-04
- DOI:
- EISSN:
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1179-1896
- ISSN:
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1175-5652
- Language:
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English
- Pubs id:
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2126942
- Local pid:
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pubs:2126942
- Deposit date:
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2025-05-28
- ARK identifier:
Terms of use
- Copyright holder:
- Crown copyright
- Copyright date:
- 2025
- Rights statement:
- © Crown 2025. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
- Licence:
- CC Attribution (CC BY)
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