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Intermuscular coherence in Parkinson's disease: relationship to bradykinesia.

Abstract:

We hypothesised that bradykinesia may be partly due to the failure of the corticomuscular system to engage in high frequency oscillatory activity in Parkinson's disease (PD). In healthy subjects such oscillations are evident in coherence between active muscles at 15--30 Hz. We therefore investigated the effects of therapeutic stimulation of the basal ganglia on this coherence and related it to changes in bradykinesia in the contralateral arm. Increases in coherence at 15--30 Hz and improvemen...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
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Journal:
Neuroreport
Volume:
12
Issue:
11
Pages:
2577-2581
Publication date:
2001-08-01
DOI:
EISSN:
1473-558X
ISSN:
0959-4965
Source identifiers:
368936
Language:
English
Keywords:
Pubs id:
pubs:368936
UUID:
uuid:08492e55-d610-4880-8706-c78c0439d882
Local pid:
pubs:368936
Deposit date:
2013-11-17

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