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Intermuscular coherence in Parkinson's disease: relationship to bradykinesia.

Abstract:

We hypothesised that bradykinesia may be partly due to the failure of the corticomuscular system to engage in high frequency oscillatory activity in Parkinson's disease (PD). In healthy subjects such oscillations are evident in coherence between active muscles at 15--30 Hz. We therefore investigated the effects of therapeutic stimulation of the basal ganglia on this coherence and related it to changes in bradykinesia in the contralateral arm. Increases in coherence at 15--30 Hz and improvemen...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Role:
Author
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Journal:
Neuroreport
Volume:
12
Issue:
11
Pages:
2577-2581
Publication date:
2001-08-05
DOI:
EISSN:
1473-558X
ISSN:
0959-4965
URN:
uuid:08492e55-d610-4880-8706-c78c0439d882
Source identifiers:
368936
Local pid:
pubs:368936

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