Effect of a very early monocular enucleation upon the development of the uncrossed retinofugal pathway in ferrets.
Monocular enucleations were done in ferret embryos before or during the earliest stages of development of the retinofugal pathway (E23-E26). The effects on the development of the uncrossed pathway from the surviving eye were assessed on embryonic day 30. This stage was chosen for two reasons: (1) we show that in normal development a substantial uncrossed component from the temporal crescent has developed by E30; and (2) the pathway cannot yet have been affected by the cell death that normally...Expand abstract
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