Journal article

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Abstract:: Realizing the potential of the diverse chemistries of natural products in biotechnology and medicine has been limited by manual analysis of experimental data through mining mass spectrometry knowledge solely captured in literature. While mass spectrometry techniques have proven well-suited for high-throughput analyses of natural products, there is no infrastructure for researchers to systematically share knowledge or analyze data. We present Global Natural Products Social molecular networking (GNPS, http://gnps.ucsd.edu), an open-access knowledge base for sharing, analysis, and community curation of raw, processed, and identified tandem mass (MS/MS) spectrometry data. GNPS further organizes, curates, and freely redistributes community-wide reference MS libraries, as well as provides a data-driven social networking infrastructure. Finally, GNPS introduces the concept of living data through crowdsourced curation of reference libraries and continuous reanalysis of public data.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Wang, M., Carver, J., Phelan, V., & O'Neill, E. (2016). Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology, 34, 828–837.

MLA Style

Wang, M., et al. “Sharing and Community Curation of Mass Spectrometry Data with Global Natural Products Social Molecular Networking.” Nature Biotechnology, vol. 34, Nature Publishing Group, 2016, pp. 828–37.

Chicago Style

Wang, M, J Carver, V Phelan, and E O'Neill. 2016. “Sharing and Community Curation of Mass Spectrometry Data with Global Natural Products Social Molecular Networking.” Nature Biotechnology 34: 828–37.
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Files:: GNPS final manuscript.pdf

(Preview, Accepted manuscript, pdf, 3.7MB, Terms of use)

Publisher copy:: 10.1038/nbt.3597

Authors

+ Wang, M More by this author

Role:: Author

+ Carver, J More by this author

Role:: Author

+ Phelan, V More by this author

Role:: Author

+ O'Neill, E More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Plant Sciences
Role:: Author

Publisher:: Nature Publishing Group
Journal:: Nature Biotechnology More from this journal
Volume:: 34
Pages:: 828–837
Publication date:: 2016-08-09
Acceptance date:: 2016-05-10
DOI:: 10.1038/nbt.3597
EISSN:: 1546-1696
ISSN:: 1087-0156

Pubs id:: pubs:633493
UUID:: uuid:083d9dcc-b906-40ee-accf-4f6e72bb1b50
Local pid:: pubs:633493
Source identifiers:: 633493
Deposit date:: 2016-07-12

Terms of use

Copyright holder:: Wang et al
Copyright date:: 2016
Notes:: Author(s) retain copyright; published by Nature Publishing Group under license. This is the accepted manuscript version of the article. The final version, with a full list of authors and funder information, is available online from Nature at: [10.1038/nbt.3597]

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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