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Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study

Abstract:

Background

Implementation of ultrasensitive HIV drug resistance tests for routine clinical use is hampered by uncertainty about the clinical relevance of drug-resistant minority variants. We assessed different detection thresholds for pretreatment drug resistance to predict an increased risk of vir... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Authors


Inzaule, SC More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Tropical Medicine
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ORCID:
0000-0002-6194-1395
Casadellà, M More by this author
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Netherlands Ministry of Foreign Affairs More from this funder
European Union More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet HIV Journal website
Volume:
5
Issue:
11
Pages:
e638-e646
Publication date:
2018-09-30
Acceptance date:
2018-06-13
DOI:
EISSN:
2352-3018
ISSN:
2405-4704
Pubs id:
pubs:949211
URN:
uri:0838ca24-ec70-4d08-ab27-b03f3213efcf
UUID:
uuid:0838ca24-ec70-4d08-ab27-b03f3213efcf
Local pid:
pubs:949211
Language:
English

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