Journal article

Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study

Abstract:: Background
Implementation of ultrasensitive HIV drug resistance tests for routine clinical use is hampered by uncertainty about the clinical relevance of drug-resistant minority variants. We assessed different detection thresholds for pretreatment drug resistance to predict an increased risk of virological failure.

Methods
We did a case-control study nested within a prospective multicountry cohort. Our study included patients from 12 clinical sites in Kenya, Nigeri... Expand abstract
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Inzaule, S., Hamers, R., Noguera-Julian, M., Casadellà, M., Parera, M., Kityo, C., Steegen, K., Naniche, D., Clotet, B., Rinke De Wit, T., Paredes, R., & Resistance, P. (2018). Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study. Lancet HIV, 5(11), e638–e646.

MLA Style

Inzaule, S, et al. “Clinically Relevant Thresholds for Ultrasensitive HIV Drug Resistance Testing: a Multi-Country Nested Case-Control Study.” Lancet HIV, vol. 5, no. 11, 2018, pp. e638–e646.

Chicago Style

Inzaule, S, R Hamers, M Noguera-Julian, et al. 2018. “Clinically Relevant Thresholds for Ultrasensitive HIV Drug Resistance Testing: a Multi-Country Nested Case-Control Study.” Lancet HIV 5 (11): e638–e646.
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Publisher copy:: 10.1016/s2352-3018(18)30177-2

Authors

+ Inzaule, S More by this author

Role:: Author

+ Hamers, R More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Sub unit:: OUCRU Oxford University Clinical Research Unit
Role:: Author

+ Noguera-Julian, M More by this author

Role:: Author
ORCID:: 0000-0002-6194-1395

+ Casadellà, M More by this author

Role:: Author

+ Parera, M More by this author

Role:: Author

More authors...

+ European Union More from this funder

+ IrsiCaixa More from this funder

+ Netherlands Ministry of Foreign Affairs More from this funder

Publisher:: Elsevier
Journal:: Lancet HIV More from this journal
Volume:: 5
Issue:: 11
Pages:: e638-e646
Publication date:: 2018-09-30
Acceptance date:: 2018-06-13
DOI:: 10.1016/s2352-3018(18)30177-2
EISSN:: 2352-3018
ISSN:: 2405-4704
Pmid:: 30282603

Language:: English
Pubs id:: pubs:949211
UUID:: uuid:0838ca24-ec70-4d08-ab27-b03f3213efcf
Local pid:: pubs:949211
Source identifiers:: 949211
Deposit date:: 2018-12-05
ARK identifier:: ark:/29072/ora_0838ca24ec704d08ab27b03f3213efcf

Terms of use

Copyright holder:: Elsevier
Copyright date:: 2018
Notes:: © 2018 Elsevier Ltd. All rights reserved.

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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