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Mechanisms of particle-induced pulmonary inflammation in a mouse model: exposure to wood dust.

Abstract:

Repeated airway exposure to wood dust has long been known to cause adverse respiratory effects such as asthma and chronic bronchitis and impairment of lung function. However, the mechanisms underlying the inflammatory responses of the airways after wood dust exposure are poorly known. We used a mouse model to elucidate the mechanisms of particle-induced inflammatory responses to fine wood dust particles. BALB/c mice were exposed to intranasally administered fine (more than 99% of the particle...

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Publisher copy:
10.1093/toxsci/kfl026

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Journal:
Toxicological sciences : an official journal of the Society of Toxicology More from this journal
Volume:
93
Issue:
1
Pages:
96-104
Publication date:
2006-09-01
DOI:
EISSN:
1096-0929
ISSN:
1096-6080
Language:
English
Keywords:
Pubs id:
pubs:387516
UUID:
uuid:081d7d57-b59a-4fb0-856f-5fcdb4c2e072
Local pid:
pubs:387516
Source identifiers:
387516
Deposit date:
2013-11-16

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