Journal article
Comparative evaluation of quetiapine plus lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in bipolar depression (CEQUEL): a 2 × 2 factorial randomised trial.
- Abstract:
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Depressive symptoms are a major cause of disability in bipolar disorder and there are few safe and effective treatments. The combination of lamotrigine plus quetiapine potentially offers improved outcomes for people with bipolar depression. We aimed to determine if combination therapy with quetiapine plus lamotrigine leads to greater improvement in depressive symptoms over 12 weeks than quetiapine monotherapy plus lamotrigine placebo.In this double-blind, randomised, placebo-controlled, paral...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 380.2KB)
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- Publisher copy:
- 10.1016/s2215-0366(15)00450-2
Authors
Funding
Medical Research Council
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Psychiatry Journal website
- Volume:
- 3
- Issue:
- 1
- Pages:
- 31-39
- Publication date:
- 2015-12-11
- DOI:
- EISSN:
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2215-0374
- ISSN:
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2215-0366
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:584229
- UUID:
-
uuid:0810007a-d0fa-4ab1-88b1-f44235c459e9
- Local pid:
- pubs:584229
- Source identifiers:
-
584229
- Deposit date:
- 2016-02-01
Terms of use
- Copyright holder:
- Geddes et al
- Copyright date:
- 2015
- Notes:
- Copyright © Geddes et al. Open Access article distributed under the terms of CC BY. Published by Elsevier. This is the publisher's version of the article. The final version is available online from Elsevier at: [10.1016/S2215-0366(15)00450-2]
- Licence:
- CC Attribution (CC BY)
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