- Abstract:
-
UNLABELLED: Here we demonstrate that primary cultures of human fetal liver cells (HFLC) reliably support infection with laboratory strains of hepatitis C virus (HCV), although levels of virus replication vary significantly between different donor cell preparations and frequently decline in a manner suggestive of active viral clearance. To investigate possible contributions of the interferon (IFN) system to control HCV infection in HFLC, we exploited the well-characterized ability of paramyxov...
Expand abstract - Publisher copy:
- 10.1002/hep.24557
-
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- Journal:
- Hepatology (Baltimore, Md.)
- Volume:
- 54
- Issue:
- 6
- Pages:
- 1901-1912
- Publication date:
- 2011-12-29
- DOI:
- EISSN:
-
1527-3350
- ISSN:
-
0270-9139
- URN:
-
uuid:080c8389-92cf-48c0-bfc4-51c8001dd473
- Source identifiers:
-
426218
- Local pid:
- pubs:426218
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.
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