Journal article

Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists.

Abstract:: The synthesis of a range of caged TRPV1 agonists and antagonists is reported. The photolysis characteristics of these compounds, when irradiated with a 355 nm laser, have been studied and in all cases the desired compound was produced. Photolysis of a caged TRPV1 agonist in cultured trigeminal neurons produced responses that were consistent with the activation of TRPV1 receptors.

Publication status:: Published

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APA Style

Ryssen, V., Avlonitis, N., Giniatullin, R., McDougall, C., Carr, J., Stanton-Humphreys, M., Borgström, E., Brown, C., Fayuk, D., Surin, A., Niittykoski, M., Khiroug, L., & Conway, S. (2009). Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. Organic and Biomolecular Chemistry, 7(22), 4695–4707.

MLA Style

Ryssen, V., et al. “Synthesis, Photolysis Studies and in Vitro Photorelease of Caged TRPV1 Agonists and Antagonists.” Organic and Biomolecular Chemistry, vol. 7, no. 22, 2009, pp. 4695–707.

Chicago Style

Ryssen, V, N Avlonitis, R Giniatullin, C McDougall, J Carr, M Stanton-Humphreys, E Borgström, et al. 2009. “Synthesis, Photolysis Studies and in Vitro Photorelease of Caged TRPV1 Agonists and Antagonists.” Organic and Biomolecular Chemistry 7 (22): 4695–4707.
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Publisher copy:: 10.1039/b914981c

Authors

+ Ryssen, V More by this author

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+ Avlonitis, N More by this author

Role:: Author

+ Giniatullin, R More by this author

Role:: Author

+ McDougall, C More by this author

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+ Carr, J More by this author

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Journal:: Organic and biomolecular chemistry More from this journal
Volume:: 7
Issue:: 22
Pages:: 4695-4707
Publication date:: 2009-11-01
DOI:: 10.1039/b914981c
EISSN:: 1477-0539
ISSN:: 1477-0520

Language:: English
Keywords:: Membrane Potentials

Light

Lasers

TRPV Cation Channels

Halogenation

Photolysis

Animals

Ligands

Rats

Capsaicin

Trigeminal Nerve

Rats, Wistar

Calcium

Intracellular Space
Pubs id:: pubs:41440
UUID:: uuid:0800043b-88b5-4bf6-9ab2-d8fd017bbcb4
Local pid:: pubs:41440
Source identifiers:: 41440
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2009

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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