Journal article
The role of astrocytes in CNS tumors: pre-clinical models and novel imaging approaches.
- Abstract:
-
Brain metastasis is a significant clinical problem, yet the mechanisms governing tumor cell extravasation across the blood-brain barrier (BBB) and CNS colonization are unclear. Astrocytes are increasingly implicated in the pathogenesis of brain metastasis but in vitro work suggests both tumoricidal and tumor-promoting roles for astrocyte-derived molecules. Also, the involvement of astrogliosis in primary brain tumor progression is under much investigation. However, translation of in vitro fin...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Frontiers in cellular neuroscience
- Volume:
- 7
- Issue:
- MAR
- Pages:
- 40
- Publication date:
- 2013-01-01
- DOI:
- EISSN:
-
1662-5102
- ISSN:
-
1662-5102
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:395963
- UUID:
-
uuid:07ff5f37-05de-4122-97cb-e582eacad284
- Local pid:
- pubs:395963
- Source identifiers:
-
395963
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2013
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