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Drugs in development for malaria

Abstract:

The last two decades have seen a surge in antimalarial drug development with product development partnerships taking a leading role. Resistance of Plasmodium falciparum to the artemisinin derivatives, piperaquine and mefloquine in Southeast Asia means new antimalarials are needed with some urgency. There are at least 13 agents in clinical development. Most of these are blood schizonticides for the treatment of uncomplicated falciparum malaria, under evaluation either singly or as part of two-...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s40265-018-0911-9

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
ORCID:
0000-0002-7620-4822
Publisher:
Springer Verlag
Journal:
Drugs More from this journal
Volume:
78
Issue:
9
Pages:
861–879
Publication date:
2018-05-25
Acceptance date:
2018-04-23
DOI:
EISSN:
1179-1950
ISSN:
0012-6667
Pmid:
29802605
Language:
English
Pubs id:
pubs:856868
UUID:
uuid:07f86b33-5434-4381-9462-c8ccefe849f3
Local pid:
pubs:856868
Source identifiers:
856868
Deposit date:
2018-06-15

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