Journal article
The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia.
- Abstract:
-
SETTING: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide. Studies in a murine model of pulmonary TB have identified a role for Toll-like receptor 4 (TLR4) in the development of chronic lung infection with Mycobacterium tuberculosis. The Asp299Gly polymorphism in the human TLR4 gene is associated with in vivo hyporesponsiveness to lipopolysaccharide (LPS) in Caucasians. OBJECTIVE: To determine whether TLR4 Asp299Gly influences LPS responses or susceptibility to pul...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Tuberculosis (Edinburgh, Scotland)
- Volume:
- 84
- Issue:
- 6
- Pages:
- 347-352
- Publication date:
- 2004-01-01
- DOI:
- EISSN:
-
1873-281X
- ISSN:
-
1472-9792
- Source identifiers:
-
32899
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:32899
- UUID:
-
uuid:07ee6d87-5e25-46d6-a019-4489b1a68932
- Local pid:
- pubs:32899
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
If you are the owner of this record, you can report an update to it here: Report update to this record