Determinants of VLDL-triglycerides production.

Journal article

PURPOSE OF REVIEW: Plasma free fatty acids (FFA) are major substrates for hepatic VLDL-triglycerides (VLDL-TG) production. In addition, it is a common belief that VLDL-TG production is a substrate driven process primarily determined by systemic FFA delivery. This review summarizes recent research of our understanding of the regulation of VLDL-TG production. RECENT FINDINGS: Recent studies have shown that increasing FFA flux is not inevitably associated with increased VLDL-TG production. Exer...

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Authors: Nielsen, S; Karpe, F

• Publication status: Published
• Journal: Current opinion in lipidology
• Volume: 23
• Issue: 4
• Pages: 321-326
• Publication date: 2012-08-01
• DOI: 10.1097/mol.0b013e3283544956
• EISSN: 1473-6535
• ISSN: 0957-9672
• Language: English
• Keywords: Insulin; Exercise; Humans; Hormones; Animals; Triglycerides; Glucagon; Fatty Acids, Nonesterified; Lipoproteins, VLDL