- Abstract:
-
RATIONALE:: Creatine is thought to be involved in the spatial and temporal buffering of ATP in energetic organs such as heart and skeletal muscle. Creatine depletion affects force generation during maximal stimulation, while reduced levels of myocardial creatine are a hallmark of the failing heart, leading to the widely held view that creatine is important at high workloads and under conditions of pathological stress. OBJECTIVE:: We therefore hypothesised that the consequences of creatine-def...
Expand abstract - Publisher copy:
- 10.1161/CIRCRESAHA.112.300725
-
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- Journal:
- Circulation Research
- Volume:
- 112
- Issue:
- 6
- Pages:
- 945-955
- Publication date:
- 2013-03-15
- DOI:
- EISSN:
-
1524-4571
- ISSN:
-
0009-7330
- URN:
-
uuid:07bda1f7-74db-494f-86f8-aaba25928f17
- Source identifiers:
-
394153
- Local pid:
- pubs:394153
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Living without creatine: Unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice
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