Journal article
Living without creatine: Unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice
- Abstract:
-
RATIONALE:: Creatine is thought to be involved in the spatial and temporal buffering of ATP in energetic organs such as heart and skeletal muscle. Creatine depletion affects force generation during maximal stimulation, while reduced levels of myocardial creatine are a hallmark of the failing heart, leading to the widely held view that creatine is important at high workloads and under conditions of pathological stress. OBJECTIVE:: We therefore hypothesised that the consequences of creatine-def...
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- Publisher copy:
- 10.1161/CIRCRESAHA.112.300725
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Bibliographic Details
- Journal:
- Circulation Research
- Volume:
- 112
- Issue:
- 6
- Pages:
- 945-955
- Publication date:
- 2013-03-15
- DOI:
- EISSN:
-
1524-4571
- ISSN:
-
0009-7330
- Source identifiers:
-
394153
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:394153
- UUID:
-
uuid:07bda1f7-74db-494f-86f8-aaba25928f17
- Local pid:
- pubs:394153
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2013
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