Journal article
A metathesis-based approach to the synthesis of 2-pyridones and pyridines.
- Abstract:
- The ring-closing metathesis reaction has been successfully employed to form a range of dihydropyridone intermediates, which are in the correct oxidation state to undergo a base-induced elimination to reveal the aromatic 2-pyridone. This mild and novel approach to six-membered heteroaromatic compounds then provides access to a wide variety of substituted pyridines in excellent overall yield.
- Publication status:
- Published
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- Publisher copy:
- 10.1021/ol702684d
Authors
- Journal:
- Organic letters More from this journal
- Volume:
- 10
- Issue:
- 2
- Pages:
- 285-288
- Publication date:
- 2008-01-01
- DOI:
- EISSN:
-
1523-7052
- ISSN:
-
1523-7060
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:34087
- UUID:
-
uuid:07b9c166-ab0b-424d-b53d-4da45e446773
- Local pid:
-
pubs:34087
- Source identifiers:
-
34087
- Deposit date:
-
2012-12-19
- ARK identifier:
Terms of use
- Copyright date:
- 2008
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