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Withdrawal of Continuous Positive Airway Pressure Therapy for 2 Weeks in Obstructive Sleep Apnoea Patients Results in Increased Circulating Platelet and Leucocyte-Derived Microvesicles.

Abstract:

In 2013 we reported that in patients with obstructive sleep apnoea (OSA), withdrawing their continuous positive airway pressure (CPAP) therapy for two weeks led to a significant increase in endothelial cell-derived microvesicles (MVs) [1]. Several other studies have found that the initiation of CPAP therapy in patients with OSA leads to a fall in endothelial [2, 3] and platelet [4, 5] MVs, but there have been no further studies investigating the impact of CPAP withdrawal in patients establis...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1159/000446077

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Department:
Oxford, MSD, NDM, NDM Experimental Medicine
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Department:
Oxford, MSD, NDM, NDM Experimental Medicine
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Publisher:
Karger Publishers Publisher's website
Journal:
Respiration Journal website
Volume:
91
Issue:
5
Pages:
412-413
Publication date:
2016-05-12
Acceptance date:
2016-04-11
DOI:
EISSN:
1423-0356
ISSN:
0025-7931
Pubs id:
pubs:623145
URN:
uri:07b4d9ed-d8a6-4f5d-b710-6e07e9854f19
UUID:
uuid:07b4d9ed-d8a6-4f5d-b710-6e07e9854f19
Local pid:
pubs:623145
Language:
English
Keywords:

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