Journal article
Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.
- Abstract:
-
The "thrifty genotype" hypothesis proposes that the high prevalence of type 2 diabetes (T2D) in Native Americans and admixed Latin Americans has a genetic basis and reflects an evolutionary adaptation to a past low calorie/high exercise lifestyle. However, identification of the gene variants underpinning this hypothesis remains elusive. Here we assessed the role of Native American ancestry, socioeconomic status (SES) and 21 candidate gene loci in susceptibility to T2D in a sample of 876 T2D c...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Version of record, pdf, 371.1KB)
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- Publisher copy:
- 10.1371/journal.pone.0033570
Authors
Funding
Harvard Medical School
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Universidad de Antioquia
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National Institutes of Health
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Colciencias
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 7
- Issue:
- 4
- Pages:
- e33570
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:07a726d8-8f90-45d0-a053-35b8e6f88c32
- Local pid:
- pubs:325406
- Source identifiers:
-
325406
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Campbell et al
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Campbell et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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