Journal article
T cells get by with a little help from their friends
- Abstract:
-
In animal models, lymphocytic choriomeningitis virus (LCMV) may be controlled after acute infection or may establish various levels of persistence. Cytotoxic responses mediated by CD8+ T cells are responsible for both initial control of LCMV and for immunopathology. As discussed in this article, there is emerging evidence that the levels of antigen to which the immune system is exposed over time are important in controlling CD8+ T cell activation, memory responses and exhaustion, and that the...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/eji.200324844
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Bibliographic Details
- Journal:
- EUROPEAN JOURNAL OF IMMUNOLOGY
- Volume:
- 34
- Issue:
- 2
- Pages:
- 313-316
- Publication date:
- 2004-02-05
- DOI:
- ISSN:
-
0014-2980
- URN:
-
uuid:07992dcd-90d5-4e87-8fe5-8dfb3641e0f5
- Source identifiers:
-
9524
- Local pid:
- pubs:9524
Terms of use
- Copyright date:
- 2004
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