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Bcl-2 expression in colorectal tumors: evidence of different pathways in sporadic and ulcerative-colitis-associated carcinomas.

Abstract:

Colorectal cancers (CRCs) differ in their age at presentation, distribution, histological features, and prognosis. If tumor biology reflects genetic events, these tumors might be expected to show differences in their genetic pathways. In this study, we investigated the role of Bcl-2 in the development of three different tumor groups. Using markers at eight different microsatellite locl, we characterized one group of 34 left-sided sporadic CRCs as replication error negative (RER-) and another ...

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Journal:
American journal of pathology More from this journal
Volume:
149
Issue:
5
Pages:
1719-1726
Publication date:
1996-11-01
EISSN:
1525-2191
ISSN:
0002-9440
Language:
English
Keywords:
Pubs id:
pubs:72308
UUID:
uuid:077373a2-af95-491f-8a7c-8ef152787c8b
Local pid:
pubs:72308
Source identifiers:
72308
Deposit date:
2012-12-19

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