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Properties of neurons in external globus pallidus can support optimal action selection

Abstract:

The external globus pallidus (GPe) is a key nucleus within basal ganglia circuits that are thought to be involved in action selection. A class of computational models assumes that, during action selection, the basal ganglia compute for all actions available in a given context the probabilities that they should be selected. These models suggest that a network of GPe and subthalamic nucleus (STN) neurons computes the normalization term in Bayes’ equation. In order to perform such computation, t...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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10.1371/journal.pcbi.1005004

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Computational Biology Journal website
Publication date:
2016-07-07
Acceptance date:
2016-06-02
DOI:
ISSN:
1553-7358
URN:
uuid:076cd0aa-b993-459d-a782-f14d261d7876
Source identifiers:
629040
Local pid:
pubs:629040

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