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Journal article

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.

Abstract:

CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its usefulness in breast cancer risk prediction. We aimed to generate tumor subtype- and age-specific risk estimates by using data from the Breast Cancer Association Consortium, including 44,777 patients with breast cancer and 42,997 controls from 33 studies genotyped for CHEK2*1100delC.C...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1200/JCO.2016.66.5844

Authors


Schmidt, MK More by this author
Hogervorst, F More by this author
van Hien, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Human Genetics Wt Centre
>Norwegian Breast Cancer Study Investigators More by this author
Publisher:
American Society of Clinical Oncology Publisher's website
Journal:
Journal of Clinical Oncology Journal website
Volume:
34
Issue:
23
Publication date:
2016-06-06
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
URN:
uuid:0750eb19-db80-4cd7-b748-af2457ad489b
Source identifiers:
628331
Local pid:
pubs:628331
Paper number:
23
Language:
English

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