Journal article icon

Journal article

Two hits revisited again.

Abstract:

INTRODUCTION AND METHODS: Since the concept of the "two hit hypothesis" was introduced over 20 years ago, a wealth of genetic data has accumulated on the mutations found at tumour suppressor loci. Perhaps surprisingly, these data conceal large gaps in our knowledge which genetic and functional studies are beginning to uncover. The "two hit hypothesis" must be updated to take account of this new information. RESULTS AND DISCUSSION: Here, we discuss both the results of recent studies and some ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1136/jmg.38.2.81
Journal:
Journal of medical genetics More from this journal
Volume:
38
Issue:
2
Pages:
81-85
Publication date:
2001-02-01
DOI:
EISSN:
1468-6244
ISSN:
0022-2593
Language:
English
Keywords:
Pubs id:
pubs:72188
UUID:
uuid:0748f18d-e11a-43de-ade0-9df0ad87b583
Local pid:
pubs:72188
Source identifiers:
72188
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP