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Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report.

Abstract:

The diagnosis and management of glucose-6-phosphate dehydrogenase (G6PD) deficiency is a crucial aspect in the current phases of malaria control and elimination, which will require the wider use of 8-aminoquinolines for both reducing Plasmodium falciparum transmission and achieving the radical cure of Plasmodium vivax. 8-aminoquinolines, such as primaquine, can induce severe haemolysis in G6PD-deficient individuals, potentially creating significant morbidity and undermining confidence in 8-am...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1475-2875-12-112

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Name:
Australian Agency for International Development
Publisher:
BioMed Central
Journal:
Malaria Journal More from this journal
Volume:
12
Issue:
1
Article number:
112
Publication date:
2013-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Language:
English
Keywords:
Pubs id:
pubs:394917
UUID:
uuid:07466e12-efd2-48bc-8b07-34a90fd00852
Local pid:
pubs:394917
Source identifiers:
394917
Deposit date:
2013-11-16

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