- Abstract:
-
Genome-wide association studies have identified many genetic variants associated with complex traits. However, at only a minority of loci have the molecular mechanisms mediating these associations been characterized. In parallel, whereas cis regulatory patterns of gene expression have been extensively explored, the identification of trans regulatory effects in humans has attracted less attention. Here we show that the type 2 diabetes and high-density lipoprotein cholesterol-associated cis-act...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/ng.833
-
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- Journal:
- NATURE GENETICS
- Volume:
- 43
- Issue:
- 6
- Pages:
- 561-U90
- Publication date:
- 2011-06-05
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:0743af3d-c0d2-4e3f-9cbb-100f097aa772
- Source identifiers:
-
149867
- Local pid:
- pubs:149867
- Language:
- English
- Keywords:
- Copyright date:
- 2011
- Notes:
- PubMed ID: 21572415
Journal article
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
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