Estimating primary care attendance rates for fever in infants after meningococcal B vaccination in England using national syndromic surveillance data

Journal article

Background

In September 2015, the United Kingdom became the first country to introduce the multicomponent group B meningococcal vaccine (4CMenB) into a national infant immunisation programme. In early clinical trials 51–61% of infants developed a fever when 4CMenB was administered with other routine vaccines. Whilst administration of prophylactic paracetamol is advised, up to 3% of parents may seek medical advice for fever following vaccination. We used research-level ... Expand abstract

Authors: Harcourt, S; Morbey, RA; Bates, C; Carter, H; Ladhani, SN

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Elsevier Publisher's website
• Journal: Vaccine Journal website
• Volume: 36
• Issue: 4
• Pages: 565-571
• Publication date: 2017-12-13
• Acceptance date: 2017-11-28
• DOI: 10.1016/j.vaccine.2017.11.076
• EISSN: 1873-2518
• ISSN: 0264-410X
• Pmid: 29246475
• Language: English
• Keywords: population surveillance; meningococcal disease; fever; medical records systems, computerised; vaccine; FFR; adverse effects