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Characterization of aortic root atherosclerosis in ApoE knockout mice: high-resolution in vivo and ex vivo MRM with histological correlation.

Abstract:

In vivo, cardiac-gated, black-blood, and ex vivo magnetic resonance microscopy (MRM) images of the aortic root, and histopathology data were obtained from 12 transgenic and wild-type (WT) mice. MRM was performed using a black-blood imaging spin-echo sequence with upstream and downstream in-flow saturation pulses to obtain aortic root images in three contrast techniques: proton density-weighted (PDW), T(1)- (T(1)W), and T(2)-weighted (T(2)W). Aortic wall thickness and area were measured and co...

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Publication status:
Published

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Publisher copy:
10.1002/mrm.10360

Authors


Itskovich, VV More by this author
Choudhury, RP More by this author
Aguinaldo, JG More by this author
Fallon, JT More by this author
Omerhodzic, S More by this author
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Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
Volume:
49
Issue:
2
Pages:
381-385
Publication date:
2003-02-05
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:07332833-c0c9-4596-99bf-3a1fbe3180b8
Source identifiers:
105994
Local pid:
pubs:105994

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