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tDCS over left M1 or DLPFC does not improve learning of a bimanual coordination task

Abstract:
Previously, transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) has resulted in improved performance in simple motor tasks. For a complex bimanual movement, studies using functional magnetic resonance imaging and transcranial magnetic stimulation indicated the involvement of the left dorsolateral prefrontal cortex (DLPFC) as well as left M1. Here we investigated the relative effect of up-regulating the cortical function in left DLPFC and left M1 with tDCS. Participants practised a complex bimanual task over four days while receiving either of five stimulation protocols: anodal tDCS applied over M1, anodal tDCS over DLPFC, sham tDCS over M1, sham tDCS over DLPFC, or no stimulation. Performance was measured at the start and end of each training day to make a distinction between acquisition and consolidation. Although task performance improved over days, no significant difference between stimulation protocols was observed, suggesting that anodal tDCS had little effect on learning the bimanual task regardless of the stimulation sites and learning phase (acquisition or consolidation). Interestingly, cognitive performance as well as corticomotor excitability did not change following stimulation. Accordingly, we found no evidence for behavioural or neurophysiological changes following tDCS over left M1 or left DLPFC in learning a complex bimanual task.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/srep35739

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
ORCID:
0000-0002-9943-9341


Publisher:
Nature Publishing Group
Journal:
Scientific Reports More from this journal
Volume:
6
Issue:
1
Pages:
35739
Publication date:
2016-10-25
Acceptance date:
2016-10-04
DOI:
EISSN:
2045-2322


Language:
English
Keywords:
Pubs id:
pubs:845781
UUID:
uuid:073168bb-0a44-4633-9797-9ef9d4cabb61
Local pid:
pubs:845781
Source identifiers:
845781
Deposit date:
2018-05-04

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