Journal article icon

Journal article

How does infliximab work in rheumatoid arthritis?

Abstract:

Since the initial characterization of tumor necrosis factor alpha (TNFalpha), it has become clear that TNFalpha has diverse biologic activity. The realization that TNFalpha plays a role in rheumatoid arthritis (RA) has led to the development of anti-TNF agents for the treatment of RA. Infliximab, a chimeric monoclonal antibody that specifically, and with high affinity, binds to TNFalpha and neutralizes the cytokine, is currently approved for the treatment of RA and Crohn's disease, another im...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1186/ar549

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Arthritis research
Volume:
4 Suppl 2
Pages:
S22-S28
Publication date:
2002-01-01
DOI:
EISSN:
1465-9913
ISSN:
1465-9905
Source identifiers:
224039
Language:
English
Keywords:
Pubs id:
pubs:224039
UUID:
uuid:07221ef6-3880-4fa5-970d-fc43f26498d9
Local pid:
pubs:224039
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP