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Macrophage clearance of apoptotic cells: a critical assessment

Abstract:

As the body continues to grow and age, it becomes essential to maintain a balance between living and dying cells. Macrophages and dendritic cells play a central role in discriminating among viable, apoptotic, and necrotic cells, as selective and efficient phagocytes, without inducing inappropriate inflammation or immune responses. A great deal has been learnt concerning clearance receptors for modified and non-self-ligands on potential targets, mediating their eventual uptake, disposal, and r...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fimmu.2018.00127

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Publisher:
Frontiers Media
Journal:
Frontiers in Immunology More from this journal
Volume:
9
Article number:
127
Publication date:
2018-01-30
Acceptance date:
2018-01-16
DOI:
EISSN:
1664-3224
ISSN:
1664-3224
Pmid:
29441073
Language:
English
Keywords:
Pubs id:
pubs:824410
UUID:
uuid:07209869-3b4b-4210-8eb6-d55f2495f90a
Local pid:
pubs:824410
Source identifiers:
824410
Deposit date:
2018-03-26

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